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NEUROLOGY 1985;35:1657
© 1985 American Academy of Neurology

Epilepsy after a first unprovoked seizure in childhood

Peter R. Camfield, MD, Carol S. Camfield, MD, J. M. Dooley, MD, J.A.R. Tibbles, MD, Tak Fung, PhD and Barry Garner, PhD

From the Departments of Pediatrics and Epidemiology, Dalhousie University, and Izaak Walton Killam Hospital for Children, Halifax, Nova Scotia, Canada.

One hundred sixty-eight children with an initial afebrile, unprovoked seizure were identified from a regional EEG laboratory. This casefinding method seemed justified because 86% of regional physicians indicated they order an EEG after a first seizure. Clinical information and recurrence rate were determined from records and telephone calls. Eighty-one percent had been seen by a pediatric neurologist. Overall, 51.8% recurred, and of those with a recurrence, 79% had additional seizures. Recurrence rates were highest in those with abnormal neurologic examination, focal spikes on EEG, and complex partial seizures. The lowest rates of recurrence followed a generalized tonic-clonic seizure, with normal EEG and normal neurologic examination. Prescription of anticonvulsants did not alter the recurrence rate.

Address correspondence and reprint requests to Dr. Camfield, I. W. Killam Hospital for Children, PO Box 3070, Halifax, Nova Scotia, Canada B3J 3G9.

Presented in part at the Child Neurology Society Annual Meeting, Phoenix, AZ. October 11, 1984.

Accepted for publication February 6, 1985.




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