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NEUROLOGY 1985;35:1499
© 1985 American Academy of Neurology

Blepharospasm, Meige syndronfie, and hemifacial Spasm

Treatment with botulinunn toxin

Joseph A. Mauriello, Jr, MD

From the Department of Ophthalmology UMDNJ-New Jersey Medical School, The Eye Institute of New Jersey, Newark. NJ.

In 34 patients with idiopathic blepharospasm, 5 with Meige syndrome, and 11 with hemifacial spasm, local injection of botulinum toxin gave temporary relief from the involuntary movements of the eyelids. Local ophthalmologic side effects were minimal. There are no known systemic side effects. The procedure had to be repeated every 12 weeks. Tolerance to the toxin did not appear.

Addres correspondence and reprint requests to Dr. Maurielln, Eye Institute of New Jersey, 15 South Ninth Street, Newark. NJ 07107.

Accepted for publication January 18, 1985.






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