Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ohta, K.
Right arrow Articles by Miyatake, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ohta, K.
Right arrow Articles by Miyatake, T.
NEUROLOGY 1985;35:1490
© 1985 American Academy of Neurology

Type 3 (adult) GM1 gangliosidosis

Case report

Keiko Ohta, MD, Shoji Tsuji, MD, Yoshikuni Mizuno, MD, Tetsushi Atsumi, MD, Tomoyasu Yahagi, MD and Tadashi Miyatake, MD

From the Department of Neurology (Drs. Ohta, Tsuji, and Miruno), Jichi Medical School, Minamikawachi-machi, Kawachi-gun, Tochigi-ken 329–04, Japan; the Department of Neurolngy (Drs. Atsumi and Miyatake), Brain Research Institute, Niigata University, Asahimachi-dori, Niigata 951, Japan; and the Department of Internal Medicine (Dr. Yahagi), Yarnagata Central Hospital, Yamagata 990, Japan.

GM1 gangliosidosis is usually a pediatric disease caused by hereditary acid P-galactosidase deficiency. There have been a few cases in adults. We saw a 51-year-old Japanese man with type 3 GM1 gangliosidosis who was manifesting dementia, dysarthria, gait disturbance, and limb rigidity. Radiologic studies showed platyspondylia, acetabular hypoplasia, and flattened femoral heads. Biochemical analysis revealed generalized acid P-galactosidase deficiency.

Address correspondence and reprint requests to Dr. Ohta. Department of Neurology, Jichi Medical School, Minamikawachi-machi. Kawachi-gun, Tochigiken. Japan 329-04.

Accepted for publication January 31,1985.




This article has been cited by other articles:


Home page
 J Geriatr Psychiatry NeurolHome page
W. E. Reichman and J. L. Cummings
Diagnosis of Rare Dementia Syndromes: An Algorithmic Approach
J Geriatr Psychiatry Neurol, April 1, 1990; 3(2): 73 - 84.
[Abstract] [PDF]

Home page
 J Child NeurolHome page
A. K. Percy
Review Article: The Inherited Neurodegenerative Disorders of Childhood: Clinical Assessment
J Child Neurol, April 1, 1987; 2(2): 82 - 97.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1985 by AAN Enterprises, Inc.