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NEUROLOGY 1985;35:1432
© 1985 American Academy of Neurology

Electrophysiologic quantification of distal polyneuropathy in diabetes

Kayode Odusote, MB, BS, Augustine Ohwovoriole, MB, BS and Oluseyi Roberts, MB, BS

From the Neurology Service (Drs. Odusote and Roberts), and Endocrine Service (Dr. Ohwovoriole), Department of Medicine. College of Medicine of the University of Lagos, Nigeria.

Electrophysiologic studies of the lower limb (reflex, motor, and sensory) were done in 50 diabetics, 30 of whom were age- and sex-matched with controls. The results were analyzed by a 0 to 9 rating—electrophysiologic polyneuropathy (EPN) score.The median EPN scores were 0.5 in controls and 3.5 in diabetics (p < 0.001). Diabetics with mild or no distal polyneuropathy (DPN) had a median EPN score of 2.4 compared with 4.7 in those with overt DPN (p < 0.0001). The EPN score correlated positively with known duration of diabetes and showed differences with age and therapy. It provides a single electrophysiologic parameter for evaluating DPN in diabetics.

Address correspondence and reprint requests to Dr. Odusote, Department of Medicine, College of Medicine of the University of Lagos. P.M.B. 12003, Lagos, Nigeria.

Accepted for publication January 15, 1985.







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