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Human ballistic arm abduction movements

Effects of L-dopa treatment in Parkinson's disease

From the Institute of Physiology, University of Florence (Drs. Fantini, Pantaleo, and Urbani) and the Department of Rehabilitation, "I Fraticini" Hospital (Drs. Baroni and Benvenuti), Florence, Italy.

In patients with Parkinson's disease who had never previously been treated with any antiparkinsonism drug, we studied the effects of L-dopa on ballistic arm abduction movement in a step-tracking task. L-Dopatreatment increased the mean velocity of the initial movement towards the target without loss of accuracy and with improved motor performance under open-loop conditions. Performance also improved in motor tasks with expected perturbation. EMG patterns of arm abduction movements showed abnormal features in untreated patients and improved after L-dopa treatment.

Address correspondence and reprint requests to Dr. Baroni, Ospedale "I Fraticini," Via dei Massoni 21,50139 Florence, Italy.

Accepted for publication November 2, 1983.

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