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NEUROLOGY 1983;33:643
© 1983 American Academy of Neurology

Amiodarone neuropathy

Alberto Martinez-Arizala, MD, Samuel M. Sobol, MD, Garland E. McCarty, MD, Buddy R. Nichols, MD and Louis Rakita, MD

Neurology Service, Department of Medicine (Drs. Martinez-Arizala and McCarty), the Physical Medicine and Rehabilitation Service (Dr. Nichols), the Cardiology Service, Department of Medicine (Dr. Sobol), Letterman Army Medical Center, Presidio of San Francisco CA, the Department of Medicine (Dr. Sobol), University of California School of Medicine, San Francisco, and the Cleveland Metropolitan General Hospital, and Case Western Reserve University (Dr. Rakita), Cleveland, OH.

Amiodarone, a drug used to treat refractory cardiac arrhythmias, produced a peripheral neuropathy in 5 of 50 cases (10%). Although the neuropathy may be severe, it tends to improve with lowering of the dosage or discontinuation of the medication.

Address correspondence and reprint requests to Technical Publications Editor, Letterman Army Medical Center, Presidio of San Francisco, CA 94129.

Accepted for publication August 17, 1982.




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P. R. Palakurthy, V. Iyer, and R. J. Meckler
Unusual Neurotoxicity Associated With Amiodarone Therapy
Arch Intern Med, May 1, 1987; 147(5): 881 - 884.
[Abstract] [PDF]