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Nonsurgical management of focal intracranial infection

Department of Neurology and Psychiatry, Tulane Medical School, the Department of Neurology, Charity Hospital of New Orleans, and the Veterans Hospital of New Orleans, LA.

Fourteen patients with focal suppurative intracranial inflammatory disease were initially treated nonsurgically. Eleven received antibiotics and corticosteroids, and three received only antibiotics. In 12, there was both clinical and computerized tomography (CT) resolution. In two patients, evolution to ring-enhancing encapsulated lesion was subsequently proved to be an encapsulated abscess that required surgical drainage, after which there was a good clinical outcome. In four patients, complete CT resolution was not evident for 2 to 6 months after completion of antibiotic therapy, although the patients had become neurologically asymptomatic prior to this.

Address correspondence and reprint requests to Dr. Weisberg, Department of Psychiatry and Neurology, Tulane Medical Center, 1415 Tulane Avenue, New Orleans, LA 70112.

Accepted for publication July 23, 1980.