HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by KOEPPEN, A. H. Articles by HANS, M. B. Search for Related Content PubMed PubMed Citation Articles by KOEPPEN, A. H. Articles by HANS, M. B.

Supranuclear ophthalmoplegia in olivopontocerebellar degeneration

From the Neurology Service, Veterans Administration Hospital, and the Department of Neurology, Albany Medical College, Albany, New York.

Autosomal dominant olivopontocerebellar degeneration was diagnosed in a family of Scottish ancestry by clinical examination and autopsy. In addition to having progressive cerebellar ataxia, head titubation, and severe dysarthria, the patients are unable to initiate saccadic eye movements. Slow pursuit movements are normal. Reflex movements of the eyes caused by passive rotation or caloric labyrinthine stimulation are not impaired but are not associated with nystagmus. The phenomenon can be classified as supranuclear pseudo-ophthalmoplegia. It differs from congenital ocular motor apraxia in age at onset and the absence of random eye movements. The anatomic lesion responsible for the defect of saccadic eye movements remains to be established.

Reprint requests should be addressed to Dr. Koeppen, Neurology Service, Veterans Administration Hospital, Albany, NY 12208.

Dr. Koeppen was the recipient of a travel grant from the Veterans Administration, Washington, DC.

Received for publication August 28, 1975.

This article has been cited by other articles:

				A. H. Koeppen, P. Coutinho, and C. Barbot Ocular Apraxia in Recessive Ataxia Arch Neurol, May 1, 2002; 59(5): 874 - 874. [Full Text] [PDF]

				K. Wessel, C. Moschner, K.-P. Wandinger, D. Kompf, and W. Heide Oculomotor Testing in the Differential Diagnosis of Degenerative Ataxic Disorders Arch Neurol, July 1, 1998; 55(7): 949 - 956. [Abstract] [Full Text] [PDF]