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Lymphocyte subpopulations in human cerebrospinal fluid

From the departments of Medicine and Surgery, Loyola University Medical Center, Maywood, Illinois.

Lymphocyte subpopulations in both human cerebrospinal fluid and peripheral blood were identified and compared by rosette techniques. In patients without neuroaxial disease, the percent distribution of Fc receptor and T-lymphocytes reflected peripheral blood values, although there was a significantly higher percentage of T cells in normal CSF. Alterations in lymphocyte cerebrospinal fluid populations were observed in various systemic and neurologic diseases.

Dr. Robinson's address is Department of Clinical Immunology, Loyola University Medical Center, 2160 S. First Ave., Maywood, IL 60153.

Received for publication October 20, 1975.

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