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NEUROLOGY 1976;26:205
© 1976 American Academy of Neurology

The use of steroids in the treatment of idiopathic polyneuritis

HERBERT M. SWICK, M.D. and MICHAEL P. McQUILLEN, M.D.

From the Departments of Neurology, University of Kentucky Medical Center, Lexington, and Medical College of Wisconsin, Milwaukee.

The efficacy of steroids in the treatment of acute idiopathic polyneuritis (Guillain-Barré syndrome) continues to be uncertain. Since 1965, 38 patients with idiopathic polyneuritis have been seen at the University of Kentucky Medical Center, and 16 of them were entered in a prospective double-blind study designed to assess the effectiveness of steroid therapy. Seriously ill patients were excluded from the study and most of them received steroids. In both the double-blind group and the entire group of patients, the time from onset of illness to recovery was significantly less in patients treated with steroids, although steroids did not alter the initial severity of illness or the duration of hospitalization.

Dr. Swick's address is Medical College of Wisconsin, Milwaukee Children's Hospital, 1700 West Wisconsin Ave., Milwaukee, Wl 53233.

This investigation was supported in part by Special Traineeship Award 1-F11-NSO 2463, NINDS, NIH.

This work was presented in part at the twenty-seventh annual meeting of the American Academy of Neurology, Bal Harbour, Florida, May 1975.

Received for publication May 27, 1975.




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