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NEUROLOGY 1976;26:1042
© 1976 American Academy of Neurology

Electrophysiologic observations in the classical form of Pelizaeus-Merzbacher disease

ROBERT J. WILKUS, M.D. and DONALD F. FARRELL, M.D.

From the Division of Electroencephalography and Clinical Neurophysiology, Department of Laboratory Medicine, and Division of Neurology, Department of Medicine, University of Washington School of Medicine, Seattle.

In a 20-year-old patient with the classic form of Pelizaeus-Merzbacher disease, electroencephalograms during wakefulness were moderately diffusely abnormal, and an overnight polygraphic sleep recording showed distorted nonrapid eye movement sleep patterns without vertex sharp waves, K-complexes, spindles, or positive occipital sharp transients. Rapid eye movement sleep could be identified. Cerebral responses evoked by light flashes, clicks, and electric stimulation of the median nerves were abnormal.

Correspondence and requests for reprints should be addressed to Dr. Wilkus, EEG Laboratory, NN283 University Hospital, SB-10, Seattle, Washington 98195.

Presented at the annual meeting of the Western Electroencephalographic Society, San Antonio, Texas, February 5, 1976.

Received for publication January 23, 1976.




This article has been cited by other articles:


Home page
 J Child NeurolHome page
J. Boulloche and J. Aicardi
Pelizaeus-Merzbacher Disease: Clinical and Nosological Study
J Child Neurol, July 1, 1986; 1(3): 233 - 239.
[Abstract] [PDF]


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