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Hypernatremia and chorea

A report of two cases

From the Department of Neurology, State University of New York, Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, New York.

The appearance of transient, generalized chorea in conjunction with brief, symmetrical myoclonic movements is described in two adult patients with hypernatremia secondary to dehydration. The association of hypernatremia and chorea is rare, even in massive salt poisoning, and has not been described previously in adults. Since both patients recovered, no pathologic material was obtained; but a speculative commentary on the possible underlying pathophysiology is included.

Dr. Sparacio's address is Department of Neurology, State University of New York, Downstate Medical Center, 450 Clarkson Ave., Brooklyn, NY 11203.

Received for publication May 7, 1975.

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