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From the Section on Neuroradiology, National Institutes of Health (Drs. Di Chiro and Hammock), and the Laboratory of Chemical Pharmacology, National Cancer Institute (Dr. Bleyer), Bethesda, Maryland.
The descent of radiopharmaceuticals injected within the right lateral ventricle toward and into the spinal subarachnoidal spaces has been followed by scintiphotographic techniques and by computerized flow analysis in a group of "normal" patients. A substantial and rapid downward progression of the albumin-tagged tracer has been observed. This progression is faster than the subarachnoidal ascent toward the convexity of the brain.
Requests for reprints should be addressed to Dr. Di Chiro, Section on Neuroradiology, National Institutes of Health, Bldg. 10, Room 2D13, Bethesda, MD 20014.
Received for publication July 13, 1975.
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